Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases

CD6 is a 105–130 kDa surface glycoprotein expressed on the majority of T cells and a subset of B cells. The human cd6 gene maps to chromosome 11, and the expression of its protein product is tightly regulated. CD6 mediates cellular adhesion migration across the endothelial and epithelial cells. In a...

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Veröffentlicht in:	Arthritis 2011, Vol.2010 (2010), p.1-9
Hauptverfasser:	Loisel, Séverine, Pers, Jacques-Olivier, Alonso-Ramirez, Ruby, Renaudineau, Yves, Youinou, Pierre, Montero, Enrique, Buors, Caroline
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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