The TAp63/BCL2 axis represents a novel mechanism of clinical aggressiveness in chronic lymphocytic leukemia

The TA-isoform of the p63 transcription factor (TAp63) has been reported to contribute to clinical aggressiveness in chronic lymphocytic leukemia (CLL) in a hitherto elusive way. Here, we sought to further understand and define the role of TAp63 in the pathophysiology of CLL. First, we found that el...

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Veröffentlicht in:Blood advances 2022-04, Vol.6 (8), p.2646-2656
Hauptverfasser: Laidou, Stamatia, Grigoriadis, Dionysios, Papanikolaou, Sofia, Foutadakis, Spyros, Ntoufa, Stavroula, Tsagiopoulou, Maria, Vatsellas, Giannis, Anagnostopoulos, Achilles, Kouvatsi, Anastasia, Stavroyianni, Niki, Psomopoulos, Fotis, Makris, Antonios M., Agelopoulos, Marios, Thanos, Dimitris, Chatzidimitriou, Anastasia, Papakonstantinou, Nikos, Stamatopoulos, Kostas
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Sprache:eng
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