The protein landscape of chronic lymphocytic leukemia

Many functional consequences of mutations on tumor phenotypes in chronic lymphocytic leukemia (CLL) are unknown. This may be in part due to a scarcity of information on the proteome of CLL. We profiled the proteome of 117 CLL patient samples with data-independent acquisition mass spectrometry and in...

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Veröffentlicht in:	Blood 2021-12, Vol.138 (24), p.2514-2525
Hauptverfasser:	Meier-Abt, Fabienne, Lu, Junyan, Cannizzaro, Ester, Pohly, Marcel F., Kummer, Sandra, Pfammatter, Sibylle, Kunz, Laura, Collins, Ben C., Nadeu, Ferran, Lee, Kwang Seok, Xue, Peng, Gwerder, Myriam, Roiss, Michael, Hüllein, Jennifer, Scheinost, Sebastian, Dietrich, Sascha, Campo, Elias, Huber, Wolfgang, Aebersold, Ruedi, Zenz, Thorsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor DEAD-box RNA Helicases - genetics Gene Expression Regulation, Leukemic Hematology Humans Immunoglobulin Heavy Chains - genetics Immunoglobulin Variable Region - genetics Leukemia, Lymphocytic, Chronic, B-Cell - genetics Life Sciences & Biomedicine Mutation Phosphoproteins - genetics Proteome - genetics RNA Splicing Factors - genetics Science & Technology Transcriptome Trisomy - genetics
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