The Cell Cycle-regulated B-Myb Transcription Factor Overcomes Cyclin-dependent Kinase Inhibitory Activity of p57 KIP2 by Interacting with Its Cyclin-binding Domain

The cell cycle-regulated B-Myb transcription factor is required for early embryonic development and is implicated in regulating cell growth and differentiation. In addition to its transcriptional regulatory properties, recent data indicate that B-Myb can release active cyclin/Cdk2 activity from the...

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Veröffentlicht in:The Journal of biological chemistry 2003-11, Vol.278 (45), p.44255-44264
Hauptverfasser: Joaquin, Manel, Watson, Roger J.
Format: Artikel
Sprache:eng
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