Preparation and preclinical evaluation of66 Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical

Abstract Introduction Integrin αv β3 plays an important role in angiogenesis and is over-expressed in tumoral endothelial cells and some other tumor cells. RGD (Arg-Gly-Asn) peptides labeled with68 Ga (t1/2 = 68 min) have showed good characteristics for imaging of αv β3 expression using positron emi...

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Veröffentlicht in:	Nuclear medicine and biology 2014, Vol.42 (2), p.109-114
Hauptverfasser:	Lopez-Rodriguez, V, Gaspar-Carcamo, R.E, Pedraza-Lopez, M, Rojas-Calderon, E.L, Arteaga de Murphy, C, Ferro-Flores, G, Avila-Rodriguez, M.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Radiology
Online-Zugang:	Volltext
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