Preliminary studies of99m Tc-memantine derivatives for NMDA receptor imaging

Abstract Introduction Novel technetium-labeled ligands,99m Tc-NCAM and99m Tc-NHAM were developed from the N -methyl- d -aspartate (NMDA) receptor agonist memantine as a lead compound by coupling with N2 S2 . This study evaluated the binding affinity and specificity of the ligands for the NMDA recept...

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Veröffentlicht in:	Nuclear medicine and biology 2012, Vol.39 (7), p.1034-1041
Hauptverfasser:	Zhou, Xingqin, Zhang, Jiankang, Yan, Chenglong, Cao, Guoxian, Zhang, Rongjun, Cai, Gangming, Jiang, Mengjun, Wang, Songpei
Format:	Artikel
Sprache:	eng
Schlagworte:	Radiology
Online-Zugang:	Volltext
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