The Prognostic Value of BRAF, cKIT and NRAS Mutations in Melanoma Patients with Brain Metastases

Abstract Background Brain metastases are a common problem in patients with melanoma but little is known about the effect of gene mutations on survival in these patients Methods We created a retrospective multi-institutional database of 823 patients with melanoma and brain metastases, diagnosed betwe...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2017
Hauptverfasser: Sperduto, Paul W., MD, MPP, FASTRO, Jiang, Wen, MD, Brown, Paul D., MD, Braunstein, Steve, MD, Sneed, Penny, MD, Wattson, Daniel A., MD, Shih, Helen A., MD, Bangdiwala, Ananta, MS, Shanley, Ryan, MS, Lockney, Natalie A., MD, Beal, Kathryn, MD, Lou, Emil, MD, PhD, Amatruda, Thomas, MD, Sperduto, William A., MS, Kirkpatrick, John P., MD, PhD, Yeh, Norman, MD, Gaspar, Laurie E., MD, MBA, FASTRO, Molitoris, Jason K., MD, Masucci, Laura, MD, Roberge, David, MD, Yu, James, MD, Chiang, Veronica, MD, Mehta, Minesh, MD, FASTRO
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Sprache:eng
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