Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management
Abstract Accurate and reproducible quantification of ventricular septal (VS) thickness in hypertrophic cardiomyopathy (HC) is essential for diagnosis, surgical planning, and risk stratification. We sought to compare VS thickness measurements using transthoracic echocardiography (TTE), transesophagea...
Gespeichert in:
| Veröffentlicht in: | The American journal of cardiology 2017 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | The American journal of cardiology |
| container_volume | |
| creator | Phelan, Dermot, MD, PhD Sperry, Brett W., MD Thavendiranathan, Paaladinesh, MD Collier, Patrick, MD, PhD Popović, Zoran B., MD, PhD Lever, Harry M., MD Smedira, Nicholas G., MD Desai, Milind Y., MD |
| description | Abstract Accurate and reproducible quantification of ventricular septal (VS) thickness in hypertrophic cardiomyopathy (HC) is essential for diagnosis, surgical planning, and risk stratification. We sought to compare VS thickness measurements using transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and cardiac magnetic resonance (CMR) in patients with HC. Prospectively reported measurements of VS thickness were compared using ANOVA and Bland-Altman plots in 90 consecutive patients with HC who underwent a TTE, TEE, and CMR within 3 months. A subset was re-measured on 2 separate occasions by 2 readers to assess inter- and intraobserver variability. There was modest correlation between modalities, with CMR and TTE measurements of VS thickness showing the greatest correlation (CMR vs. TTE, r=0.70; CMR vs. TEE, r=0.60; TTE vs. TEE, r= 0.56). Smaller measurements were seen using CMR vs. either echocardiographic modality (13% smaller vs. TEE; 8% smaller vs. TTE, p |
| doi_str_mv | 10.1016/j.amjcard.2017.02.009 |
| format | Article |
| fullrecord | <record><control><sourceid>elsevier</sourceid><recordid>TN_cdi_elsevier_clinicalkeyesjournals_1_s2_0_S0002914917301959</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002914917301959</els_id><sourcerecordid>1_s2_0_S0002914917301959</sourcerecordid><originalsourceid>FETCH-elsevier_clinicalkeyesjournals_1_s2_0_S00029149173019593</originalsourceid><addsrcrecordid>eNqlUEtOwzAQ9QIkyucISHOBBjulrbJhE0BlUQkpwDYaOY47wbEj20HK3TgcTsQNupp5n3kzGsbuBc8EF7uHLsO-k-ibLOdin_E847y4YCvOeb4uxGNxxa5D6BIUYrtbsd_S9QN6Cs6Ca-FL2ehJjgY9VGqIaOCoMIxe9UkJQBYO06B89G44kYQybSLXT27AeJrgHSMtvk_bKK8dWQ3V6DXJOWhSMiYvjGHmj6OJ1LsGDcUJ3nrUM4u2Sf1g0kQkZwO0zsMzobYuUFjkI1rUyz237LJFE9Tdf71hT68vH-VhrRL4IeVracjOy7_VpELnRm-TrxZ1yGteV_NT5p-I_YaLYltszg74A4vPgcU</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management</title><source>Elsevier ScienceDirect Journals</source><source>ProQuest Central UK/Ireland</source><creator>Phelan, Dermot, MD, PhD ; Sperry, Brett W., MD ; Thavendiranathan, Paaladinesh, MD ; Collier, Patrick, MD, PhD ; Popović, Zoran B., MD, PhD ; Lever, Harry M., MD ; Smedira, Nicholas G., MD ; Desai, Milind Y., MD</creator><creatorcontrib>Phelan, Dermot, MD, PhD ; Sperry, Brett W., MD ; Thavendiranathan, Paaladinesh, MD ; Collier, Patrick, MD, PhD ; Popović, Zoran B., MD, PhD ; Lever, Harry M., MD ; Smedira, Nicholas G., MD ; Desai, Milind Y., MD</creatorcontrib><description>Abstract Accurate and reproducible quantification of ventricular septal (VS) thickness in hypertrophic cardiomyopathy (HC) is essential for diagnosis, surgical planning, and risk stratification. We sought to compare VS thickness measurements using transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and cardiac magnetic resonance (CMR) in patients with HC. Prospectively reported measurements of VS thickness were compared using ANOVA and Bland-Altman plots in 90 consecutive patients with HC who underwent a TTE, TEE, and CMR within 3 months. A subset was re-measured on 2 separate occasions by 2 readers to assess inter- and intraobserver variability. There was modest correlation between modalities, with CMR and TTE measurements of VS thickness showing the greatest correlation (CMR vs. TTE, r=0.70; CMR vs. TEE, r=0.60; TTE vs. TEE, r= 0.56). Smaller measurements were seen using CMR vs. either echocardiographic modality (13% smaller vs. TEE; 8% smaller vs. TTE, p<0.001 for both). The variability of measures between modalities was not correlated with the degree of VS thickness. There was significantly lower intraobserver variability with CMR vs. echocardiography (p=0.01 for both), but no difference in interobserver variability. CMR delineated a different area of maximal VS thickness other than the basal anteroseptum more frequently than echocardiography (44% of cases versus 24% for TTE and 11% for TEE). In conclusion, CMR assessment of VS thickness differs significantly from echocardiography in patients with HC, with a systemic bias towards lower measurements seen with CMR.</description><identifier>ISSN: 0002-9149</identifier><identifier>DOI: 10.1016/j.amjcard.2017.02.009</identifier><language>eng</language><subject>Cardiovascular</subject><ispartof>The American journal of cardiology, 2017</ispartof><rights>Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids></links><search><creatorcontrib>Phelan, Dermot, MD, PhD</creatorcontrib><creatorcontrib>Sperry, Brett W., MD</creatorcontrib><creatorcontrib>Thavendiranathan, Paaladinesh, MD</creatorcontrib><creatorcontrib>Collier, Patrick, MD, PhD</creatorcontrib><creatorcontrib>Popović, Zoran B., MD, PhD</creatorcontrib><creatorcontrib>Lever, Harry M., MD</creatorcontrib><creatorcontrib>Smedira, Nicholas G., MD</creatorcontrib><creatorcontrib>Desai, Milind Y., MD</creatorcontrib><title>Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management</title><title>The American journal of cardiology</title><description>Abstract Accurate and reproducible quantification of ventricular septal (VS) thickness in hypertrophic cardiomyopathy (HC) is essential for diagnosis, surgical planning, and risk stratification. We sought to compare VS thickness measurements using transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and cardiac magnetic resonance (CMR) in patients with HC. Prospectively reported measurements of VS thickness were compared using ANOVA and Bland-Altman plots in 90 consecutive patients with HC who underwent a TTE, TEE, and CMR within 3 months. A subset was re-measured on 2 separate occasions by 2 readers to assess inter- and intraobserver variability. There was modest correlation between modalities, with CMR and TTE measurements of VS thickness showing the greatest correlation (CMR vs. TTE, r=0.70; CMR vs. TEE, r=0.60; TTE vs. TEE, r= 0.56). Smaller measurements were seen using CMR vs. either echocardiographic modality (13% smaller vs. TEE; 8% smaller vs. TTE, p<0.001 for both). The variability of measures between modalities was not correlated with the degree of VS thickness. There was significantly lower intraobserver variability with CMR vs. echocardiography (p=0.01 for both), but no difference in interobserver variability. CMR delineated a different area of maximal VS thickness other than the basal anteroseptum more frequently than echocardiography (44% of cases versus 24% for TTE and 11% for TEE). In conclusion, CMR assessment of VS thickness differs significantly from echocardiography in patients with HC, with a systemic bias towards lower measurements seen with CMR.</description><subject>Cardiovascular</subject><issn>0002-9149</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqlUEtOwzAQ9QIkyucISHOBBjulrbJhE0BlUQkpwDYaOY47wbEj20HK3TgcTsQNupp5n3kzGsbuBc8EF7uHLsO-k-ibLOdin_E847y4YCvOeb4uxGNxxa5D6BIUYrtbsd_S9QN6Cs6Ca-FL2ehJjgY9VGqIaOCoMIxe9UkJQBYO06B89G44kYQybSLXT27AeJrgHSMtvk_bKK8dWQ3V6DXJOWhSMiYvjGHmj6OJ1LsGDcUJ3nrUM4u2Sf1g0kQkZwO0zsMzobYuUFjkI1rUyz237LJFE9Tdf71hT68vH-VhrRL4IeVracjOy7_VpELnRm-TrxZ1yGteV_NT5p-I_YaLYltszg74A4vPgcU</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>Phelan, Dermot, MD, PhD</creator><creator>Sperry, Brett W., MD</creator><creator>Thavendiranathan, Paaladinesh, MD</creator><creator>Collier, Patrick, MD, PhD</creator><creator>Popović, Zoran B., MD, PhD</creator><creator>Lever, Harry M., MD</creator><creator>Smedira, Nicholas G., MD</creator><creator>Desai, Milind Y., MD</creator><scope/></search><sort><creationdate>2017</creationdate><title>Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management</title><author>Phelan, Dermot, MD, PhD ; Sperry, Brett W., MD ; Thavendiranathan, Paaladinesh, MD ; Collier, Patrick, MD, PhD ; Popović, Zoran B., MD, PhD ; Lever, Harry M., MD ; Smedira, Nicholas G., MD ; Desai, Milind Y., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-elsevier_clinicalkeyesjournals_1_s2_0_S00029149173019593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Cardiovascular</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Phelan, Dermot, MD, PhD</creatorcontrib><creatorcontrib>Sperry, Brett W., MD</creatorcontrib><creatorcontrib>Thavendiranathan, Paaladinesh, MD</creatorcontrib><creatorcontrib>Collier, Patrick, MD, PhD</creatorcontrib><creatorcontrib>Popović, Zoran B., MD, PhD</creatorcontrib><creatorcontrib>Lever, Harry M., MD</creatorcontrib><creatorcontrib>Smedira, Nicholas G., MD</creatorcontrib><creatorcontrib>Desai, Milind Y., MD</creatorcontrib><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Phelan, Dermot, MD, PhD</au><au>Sperry, Brett W., MD</au><au>Thavendiranathan, Paaladinesh, MD</au><au>Collier, Patrick, MD, PhD</au><au>Popović, Zoran B., MD, PhD</au><au>Lever, Harry M., MD</au><au>Smedira, Nicholas G., MD</au><au>Desai, Milind Y., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management</atitle><jtitle>The American journal of cardiology</jtitle><date>2017</date><risdate>2017</risdate><issn>0002-9149</issn><abstract>Abstract Accurate and reproducible quantification of ventricular septal (VS) thickness in hypertrophic cardiomyopathy (HC) is essential for diagnosis, surgical planning, and risk stratification. We sought to compare VS thickness measurements using transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and cardiac magnetic resonance (CMR) in patients with HC. Prospectively reported measurements of VS thickness were compared using ANOVA and Bland-Altman plots in 90 consecutive patients with HC who underwent a TTE, TEE, and CMR within 3 months. A subset was re-measured on 2 separate occasions by 2 readers to assess inter- and intraobserver variability. There was modest correlation between modalities, with CMR and TTE measurements of VS thickness showing the greatest correlation (CMR vs. TTE, r=0.70; CMR vs. TEE, r=0.60; TTE vs. TEE, r= 0.56). Smaller measurements were seen using CMR vs. either echocardiographic modality (13% smaller vs. TEE; 8% smaller vs. TTE, p<0.001 for both). The variability of measures between modalities was not correlated with the degree of VS thickness. There was significantly lower intraobserver variability with CMR vs. echocardiography (p=0.01 for both), but no difference in interobserver variability. CMR delineated a different area of maximal VS thickness other than the basal anteroseptum more frequently than echocardiography (44% of cases versus 24% for TTE and 11% for TEE). In conclusion, CMR assessment of VS thickness differs significantly from echocardiography in patients with HC, with a systemic bias towards lower measurements seen with CMR.</abstract><doi>10.1016/j.amjcard.2017.02.009</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 2017 |
| issn | 0002-9149 |
| language | eng |
| recordid | cdi_elsevier_clinicalkeyesjournals_1_s2_0_S0002914917301959 |
| source | Elsevier ScienceDirect Journals; ProQuest Central UK/Ireland |
| subjects | Cardiovascular |
| title | Comparison of Ventricular Septal Measurements in Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy using Multimodality Imaging and Implications for Diagnosis and Management |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T11%3A15%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-elsevier&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20Ventricular%20Septal%20Measurements%20in%20Hypertrophic%20Cardiomyopathy%20Patients%20Undergoing%20Surgical%20Myectomy%20using%20Multimodality%20Imaging%20and%20Implications%20for%20Diagnosis%20and%20Management&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Phelan,%20Dermot,%20MD,%20PhD&rft.date=2017&rft.issn=0002-9149&rft_id=info:doi/10.1016/j.amjcard.2017.02.009&rft_dat=%3Celsevier%3E1_s2_0_S0002914917301959%3C/elsevier%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_els_id=1_s2_0_S0002914917301959&rfr_iscdi=true |