Effects of Heme Proteins on Nitric Oxide Levels and Cell Viability in Isolated PMNs: A Mechanism of Toxicity

Isolated human PMNs served as a model to determine oxyhemoglobin (oxyHb) binding and the effects of oxymyoglobin (oxyMb) or oxyHb on production of both nitric oxide (NO) and superoxide (O2-) and the resulting cytotoxicity. Physiologically relevant concentrations of NO and H2O2 oxidized, to a similar...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Cassidy, Richard A, Burleson, David G, Deldado, Angel V, Kohler, Dennis J, Salin, Marvin L, Pruitt, Jr, Basil A
Format:	Report
Sprache:	eng
Schlagworte:	APOPTOSIS Biochemistry BLOOD TRANSFUSION CELLS(BIOLOGY) CYTOTOXINS DEOXYRIBONUCLEIC ACIDS DNA STRAND BREAKS FILTRATION GLUTATHIONE HEMOGLOBIN IMMUNOSUPPRESSION INFECTIOUS DISEASES INHIBITORS ISOLATION LIPOPOLYSACCHARIDES Medicine and Medical Research MEMBRANES(BIOLOGY) MYOGLOBIN NECROSIS NEOPLASMS NITRIC OXIDE OXYHB(OXYHEMOGLOBIN) PATHOLOGY POLYMORPHONUCLEAR NEUTROPHILS PROTEINS SUPEROXIDE SUPEROXIDE DISMUTASE SYNTHASES Toxicology VIABILITY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!