Evaluation of ADD392124 for the Delayed Treatment of Nerve Agent-Induced Status Epilepticus Seizures

ADD392124 was identified by the Anticonvulsant Screening Program as being able to control benzodiazepine-resistant status epilepticus seizures. We evaluated the ability of ADD392124 to control seizures induced by the nerve agent soman. Rats were exposed to a convulsant dose of soman. Seizures were a...

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Hauptverfasser:	McDonough, John H, Van Shura, Kerry E, Lyman, Megan E, Eisner, Claire G, Mazza, Amelia, Kan, Robert K, Shih, Tsung-Ming
Format:	Report
Sprache:	eng
Schlagworte:	ANTICONVULSANTS Chemical, Biological and Radiological Warfare CONVULSIVE DISORDERS DELAYED TREATMENT GD AGENT MEDICAL COUNTERMEASURES NERVE AGENTS Pharmacology SEIZURES SOMAN THERAPY
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