Scrub Typhus Vaccine Candidate Kp r56 Induces Humoral and Cellular Immune Responses in Cynomolgus Monkeys

A truncated recombinant 56-kDa outer membrane protein of the Karp strain of Orientia tsutsugamushi (Kp r56) was evaluated in cynomolgus monkeys (Macaca fascicularis) for immunogenicity and safety as a vaccine candidate for the prevention of scrub typhus. This recombinant antigen induced strong humor...

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Hauptverfasser:	Chattopadhyay, Suchismita, Jiang, Ju, Chan, Teik-Chye, Manetz, T S, Chao, Chien-Chung, Ching, Wei-Mei, Richards, Allen L
Format:	Report
Sprache:	eng
Schlagworte:	ANTIGENS Biology CELLS(BIOLOGY) HUMORAL IMMUNITY INFECTIOUS DISEASES Medicine and Medical Research MONKEYS Pharmacology REPRINTS RESPONSE(BIOLOGY) SCRUB TYPHUS TYPHUS RICKETTSIAE VACCINES
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