The Role of Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPs) in IGF-Mediated Tumorigenicity
The insulin-like growth factor (IGF) system has been shown to play an important role in the development and progression of breast cancer. IGF-l binds with high affinity to a family of proteins called the IGF binding proteins (IGFBPs), which act as natural inhibitors of IGF-l through sequestration fr...
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