A New Class of Serine and Cysteine Protease Inhibitor with Chemotherapeutic Potential

Metastasis of cancer is dependent on a variety of biologically active compounds including serine proteases. Inhibition of proteases such as plasmin is a potential route for both suppression of metastatic lesions and control of primary tumor growth. Synthesis of tetrahydrothiopyran-4-one based inhibi...

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