Therapeutic Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Accelerates Hemopoietic Regeneration and Enhances Survival in a Murine Model of Radiation-Induced Myelosuppression

The primary cause of death after radiation exposure is infection resulting from myelosuppression. Because granulocytes play a critical role in host defense against infection and because granulocyte proliferation and differentiation are enhanced by granulocyte colony-stimulating factor (G-CSF), this...

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