Investigation of the Bioavailability of WR-158,122

The purpose of the work performed on this contract was to prepare formulations designed to improve the oral bioavailability of the potent antimalarial, 2,4-diamino-6-(2-naphthylsulfonyl)quinazoline (WR-158,122). During the first six months of the program formulations of the drug were prepared with w...

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Bibliographische Detailangaben

Hauptverfasser:	Granchelli,Felix E, Yesair,David W, Chadwick,Majory, Braun,James W, Rachwall,Peter C
Format:	Report
Sprache:	eng
Schlagworte:	ANTIMALARIALS BIOLOGICAL ABSORPTION DOSAGE Dosage forms DRUGS FORMULATIONS INGESTION(PHYSIOLOGY) NAPHTHALENES NITROGEN HETEROCYCLIC COMPOUNDS Pharmacology Quinazoline/diamino-naphthylsulfonyl SOLUBILITY
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