Characterization of the Polypeptides in Varicella Zoster Virus - Infected Cells

The structural and functional proteins expressed by Varicella-Zoster virus (VZV), the agent that causes chicfcenpox and shingles, wereexamined at the infected cell level and the virion level. To accomplishthis a new cell line of human foreskin fibroblasts was employed for thegrowth of the virus. In...

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description The structural and functional proteins expressed by Varicella-Zoster virus (VZV), the agent that causes chicfcenpox and shingles, wereexamined at the infected cell level and the virion level. To accomplishthis a new cell line of human foreskin fibroblasts was employed for thegrowth of the virus. In addition a unique virion isolation techniquewas developed using sucrose zonal centrifugation followed by a combinationof equilibrium-viscosity sedimentation with potassium tartrateglycerolgradients.
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source DTIC Technical Reports
subjects cells(biology)
chickenpox
fibroblasts
HERPESVIRIDAE
Herpetic viruses
peptides
polypeptides
proteins
shingles
virion
vzv(varicella-zoster virus)
title Characterization of the Polypeptides in Varicella Zoster Virus - Infected Cells
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