INJURY ACCUMULATION AND RECOVERY IN SHEEP EXPOSED TO PROTRACTED CO60 GAMMA RADIATION

A modified split-dose technique was used to measure the accumulation of injury during protracted exposures of the domestic sheep to Cobalt-60 gamma radiation. An initial or conditioning exposure of 165 R was given at 0.5, 0.95, 1.85, and 3.94 R/hr, and the acute exposure LD50/60 was determined immed...

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Hauptverfasser: Hanks,Gerald E, Ainsworth,John E, Leong,George F, Nachtwey,D. Stuart, Page,Norbert P
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creator Hanks,Gerald E
Ainsworth,John E
Leong,George F
Nachtwey,D. Stuart
Page,Norbert P
description A modified split-dose technique was used to measure the accumulation of injury during protracted exposures of the domestic sheep to Cobalt-60 gamma radiation. An initial or conditioning exposure of 165 R was given at 0.5, 0.95, 1.85, and 3.94 R/hr, and the acute exposure LD50/60 was determined immediately thereafter. These studies indicate that there is a dose rate threshold for injury accumulation under these conditions or protracted irradiation and that the threshold lies between 1.0 and 1.5 R/hr. Recovery from injury accumulated during protracted exposures has been studied by determining the LD50/60 at various times after protracted exposures. These studies indicate a rapid recovery without a lag period that proceeds to a transient acquired radioresistance 15 days after the conclusion of the protracted irradiation. (Author)
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Stuart ; Page,Norbert P ; NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF</creatorcontrib><description>A modified split-dose technique was used to measure the accumulation of injury during protracted exposures of the domestic sheep to Cobalt-60 gamma radiation. An initial or conditioning exposure of 165 R was given at 0.5, 0.95, 1.85, and 3.94 R/hr, and the acute exposure LD50/60 was determined immediately thereafter. These studies indicate that there is a dose rate threshold for injury accumulation under these conditions or protracted irradiation and that the threshold lies between 1.0 and 1.5 R/hr. Recovery from injury accumulated during protracted exposures has been studied by determining the LD50/60 at various times after protracted exposures. These studies indicate a rapid recovery without a lag period that proceeds to a transient acquired radioresistance 15 days after the conclusion of the protracted irradiation. 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These studies indicate a rapid recovery without a lag period that proceeds to a transient acquired radioresistance 15 days after the conclusion of the protracted irradiation. (Author)</description><subject>DOSE RATE</subject><subject>GAMMA RAYS</subject><subject>MAMMALS</subject><subject>RADIATION DOSAGE</subject><subject>RADIATION INJURIES</subject><subject>Radiobiology</subject><subject>RECOVERY</subject><subject>SPLIT-DOSE TECHNIQUE</subject><subject>THRESHOLDS(PHYSIOLOGY)</subject><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>1967</creationdate><recordtype>report</recordtype><sourceid>1RU</sourceid><recordid>eNrjZAjx9PMKDYpUcHR2DvUN9XEM8fT3U3D0c1EIcnX2D3MFynj6KQR7uLoGKLhGBPgHu7oohPgrBAT5hwQ5OocAec7-ZgYK7o6-vo4KQY4unmADeBhY0xJzilN5oTQ3g4yba4izh25KSWZyfHFJZl5qSbyji4GZiYWJoaUxAWkAS3UtEg</recordid><startdate>19670306</startdate><enddate>19670306</enddate><creator>Hanks,Gerald E</creator><creator>Ainsworth,John E</creator><creator>Leong,George F</creator><creator>Nachtwey,D. 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Stuart</creatorcontrib><creatorcontrib>Page,Norbert P</creatorcontrib><creatorcontrib>NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF</creatorcontrib><collection>DTIC Technical Reports</collection><collection>DTIC STINET</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Hanks,Gerald E</au><au>Ainsworth,John E</au><au>Leong,George F</au><au>Nachtwey,D. Stuart</au><au>Page,Norbert P</au><aucorp>NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF</aucorp><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><btitle>INJURY ACCUMULATION AND RECOVERY IN SHEEP EXPOSED TO PROTRACTED CO60 GAMMA RADIATION</btitle><date>1967-03-06</date><risdate>1967</risdate><abstract>A modified split-dose technique was used to measure the accumulation of injury during protracted exposures of the domestic sheep to Cobalt-60 gamma radiation. An initial or conditioning exposure of 165 R was given at 0.5, 0.95, 1.85, and 3.94 R/hr, and the acute exposure LD50/60 was determined immediately thereafter. These studies indicate that there is a dose rate threshold for injury accumulation under these conditions or protracted irradiation and that the threshold lies between 1.0 and 1.5 R/hr. Recovery from injury accumulated during protracted exposures has been studied by determining the LD50/60 at various times after protracted exposures. These studies indicate a rapid recovery without a lag period that proceeds to a transient acquired radioresistance 15 days after the conclusion of the protracted irradiation. (Author)</abstract><oa>free_for_read</oa></addata></record>
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source DTIC Technical Reports
subjects DOSE RATE
GAMMA RAYS
MAMMALS
RADIATION DOSAGE
RADIATION INJURIES
Radiobiology
RECOVERY
SPLIT-DOSE TECHNIQUE
THRESHOLDS(PHYSIOLOGY)
title INJURY ACCUMULATION AND RECOVERY IN SHEEP EXPOSED TO PROTRACTED CO60 GAMMA RADIATION
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