SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES
The capability of rapidly polymerizing monomeric alpha cyanoacrylates to adhere firmly to moist surfaces has evoked considerable medical interest in their potentialities as hemostatic agents and tissue adhesives for closure of wounds in place of, or as adjuncts to, the conventional surgical sutures....
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Report |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Leonard, Fred kulkarni,Ramchandra K Brandes,George Nelson,Joshua |
| description | The capability of rapidly polymerizing monomeric alpha cyanoacrylates to adhere firmly to moist surfaces has evoked considerable medical interest in their potentialities as hemostatic agents and tissue adhesives for closure of wounds in place of, or as adjuncts to, the conventional surgical sutures. A report is given on the synthesis of the homologous series of alkyl-alpha-cyanoacrylates, their physical properties with respect to purity and also the kinetics of in vitro degradation of poly-alkyl-alpha-cyanoacrylates in the presence of water, both in the heterogeneous and homogeneous phases. Other important findings on the mode of polymerization are given and comparison of in vitro with the in vivo degradation results are made. (Author) |
| format | Report |
| fullrecord | <record><control><sourceid>dtic_1RU</sourceid><recordid>TN_cdi_dtic_stinet_AD0634617</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AD0634617</sourcerecordid><originalsourceid>FETCH-dtic_stinet_AD06346173</originalsourceid><addsrcrecordid>eNrjZLAJjvQL8XAN9gxWcPRzUXBxdQ9ydHEM8fT3U_B3Uwjw94lUcPTxjvQBkgEejgrOkY5-_o7OQZE-jiGuwTwMrGmJOcWpvFCam0HGzTXE2UM3pSQzOb64JDMvtSTe0cXAzNjEzNDcmIA0AG-hJrA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>report</recordtype></control><display><type>report</type><title>SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES</title><source>DTIC Technical Reports</source><creator>Leonard, Fred ; kulkarni,Ramchandra K ; Brandes,George ; Nelson,Joshua</creator><creatorcontrib>Leonard, Fred ; kulkarni,Ramchandra K ; Brandes,George ; Nelson,Joshua ; ARMY MEDICAL BIOMECHANICAL RESEARCH LAB WALTER REED ARMY MEDICAL CENTER WASHINGTON D C</creatorcontrib><description>The capability of rapidly polymerizing monomeric alpha cyanoacrylates to adhere firmly to moist surfaces has evoked considerable medical interest in their potentialities as hemostatic agents and tissue adhesives for closure of wounds in place of, or as adjuncts to, the conventional surgical sutures. A report is given on the synthesis of the homologous series of alkyl-alpha-cyanoacrylates, their physical properties with respect to purity and also the kinetics of in vitro degradation of poly-alkyl-alpha-cyanoacrylates in the presence of water, both in the heterogeneous and homogeneous phases. Other important findings on the mode of polymerization are given and comparison of in vitro with the in vivo degradation results are made. (Author)</description><language>eng</language><subject>ACRYLIC RESINS ; ADHESIVES ; Adhesives, Seals and Binders ; CHEMICAL REACTIONS ; DEGRADATION ; IN VITRO ANALYSIS ; IN VIVO ANALYSIS ; Medical Facilities, Equipment and Supplies ; NITRILES ; PHYSICAL PROPERTIES ; Polymer Chemistry ; POLYMERIZATION ; POLYMERS ; REACTION KINETICS ; TISSUE ADHESIVES ; TISSUES(BIOLOGY)</subject><creationdate>1966</creationdate><rights>APPROVED FOR PUBLIC RELEASE</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,780,885,27567,27568</link.rule.ids><linktorsrc>$$Uhttps://apps.dtic.mil/sti/citations/AD0634617$$EView_record_in_DTIC$$FView_record_in_$$GDTIC$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Leonard, Fred</creatorcontrib><creatorcontrib>kulkarni,Ramchandra K</creatorcontrib><creatorcontrib>Brandes,George</creatorcontrib><creatorcontrib>Nelson,Joshua</creatorcontrib><creatorcontrib>ARMY MEDICAL BIOMECHANICAL RESEARCH LAB WALTER REED ARMY MEDICAL CENTER WASHINGTON D C</creatorcontrib><title>SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES</title><description>The capability of rapidly polymerizing monomeric alpha cyanoacrylates to adhere firmly to moist surfaces has evoked considerable medical interest in their potentialities as hemostatic agents and tissue adhesives for closure of wounds in place of, or as adjuncts to, the conventional surgical sutures. A report is given on the synthesis of the homologous series of alkyl-alpha-cyanoacrylates, their physical properties with respect to purity and also the kinetics of in vitro degradation of poly-alkyl-alpha-cyanoacrylates in the presence of water, both in the heterogeneous and homogeneous phases. Other important findings on the mode of polymerization are given and comparison of in vitro with the in vivo degradation results are made. (Author)</description><subject>ACRYLIC RESINS</subject><subject>ADHESIVES</subject><subject>Adhesives, Seals and Binders</subject><subject>CHEMICAL REACTIONS</subject><subject>DEGRADATION</subject><subject>IN VITRO ANALYSIS</subject><subject>IN VIVO ANALYSIS</subject><subject>Medical Facilities, Equipment and Supplies</subject><subject>NITRILES</subject><subject>PHYSICAL PROPERTIES</subject><subject>Polymer Chemistry</subject><subject>POLYMERIZATION</subject><subject>POLYMERS</subject><subject>REACTION KINETICS</subject><subject>TISSUE ADHESIVES</subject><subject>TISSUES(BIOLOGY)</subject><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>1966</creationdate><recordtype>report</recordtype><sourceid>1RU</sourceid><recordid>eNrjZLAJjvQL8XAN9gxWcPRzUXBxdQ9ydHEM8fT3U_B3Uwjw94lUcPTxjvQBkgEejgrOkY5-_o7OQZE-jiGuwTwMrGmJOcWpvFCam0HGzTXE2UM3pSQzOb64JDMvtSTe0cXAzNjEzNDcmIA0AG-hJrA</recordid><startdate>196606</startdate><enddate>196606</enddate><creator>Leonard, Fred</creator><creator>kulkarni,Ramchandra K</creator><creator>Brandes,George</creator><creator>Nelson,Joshua</creator><scope>1RU</scope><scope>BHM</scope></search><sort><creationdate>196606</creationdate><title>SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES</title><author>Leonard, Fred ; kulkarni,Ramchandra K ; Brandes,George ; Nelson,Joshua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-dtic_stinet_AD06346173</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng</language><creationdate>1966</creationdate><topic>ACRYLIC RESINS</topic><topic>ADHESIVES</topic><topic>Adhesives, Seals and Binders</topic><topic>CHEMICAL REACTIONS</topic><topic>DEGRADATION</topic><topic>IN VITRO ANALYSIS</topic><topic>IN VIVO ANALYSIS</topic><topic>Medical Facilities, Equipment and Supplies</topic><topic>NITRILES</topic><topic>PHYSICAL PROPERTIES</topic><topic>Polymer Chemistry</topic><topic>POLYMERIZATION</topic><topic>POLYMERS</topic><topic>REACTION KINETICS</topic><topic>TISSUE ADHESIVES</topic><topic>TISSUES(BIOLOGY)</topic><toplevel>online_resources</toplevel><creatorcontrib>Leonard, Fred</creatorcontrib><creatorcontrib>kulkarni,Ramchandra K</creatorcontrib><creatorcontrib>Brandes,George</creatorcontrib><creatorcontrib>Nelson,Joshua</creatorcontrib><creatorcontrib>ARMY MEDICAL BIOMECHANICAL RESEARCH LAB WALTER REED ARMY MEDICAL CENTER WASHINGTON D C</creatorcontrib><collection>DTIC Technical Reports</collection><collection>DTIC STINET</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Leonard, Fred</au><au>kulkarni,Ramchandra K</au><au>Brandes,George</au><au>Nelson,Joshua</au><aucorp>ARMY MEDICAL BIOMECHANICAL RESEARCH LAB WALTER REED ARMY MEDICAL CENTER WASHINGTON D C</aucorp><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><btitle>SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES</btitle><date>1966-06</date><risdate>1966</risdate><abstract>The capability of rapidly polymerizing monomeric alpha cyanoacrylates to adhere firmly to moist surfaces has evoked considerable medical interest in their potentialities as hemostatic agents and tissue adhesives for closure of wounds in place of, or as adjuncts to, the conventional surgical sutures. A report is given on the synthesis of the homologous series of alkyl-alpha-cyanoacrylates, their physical properties with respect to purity and also the kinetics of in vitro degradation of poly-alkyl-alpha-cyanoacrylates in the presence of water, both in the heterogeneous and homogeneous phases. Other important findings on the mode of polymerization are given and comparison of in vitro with the in vivo degradation results are made. (Author)</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_dtic_stinet_AD0634617 |
| source | DTIC Technical Reports |
| subjects | ACRYLIC RESINS ADHESIVES Adhesives, Seals and Binders CHEMICAL REACTIONS DEGRADATION IN VITRO ANALYSIS IN VIVO ANALYSIS Medical Facilities, Equipment and Supplies NITRILES PHYSICAL PROPERTIES Polymer Chemistry POLYMERIZATION POLYMERS REACTION KINETICS TISSUE ADHESIVES TISSUES(BIOLOGY) |
| title | SYNTHESIS AND DEGRADATION OF POLY ALKYL ALPHA CYANOACRYLATES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T08%3A20%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-dtic_1RU&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.btitle=SYNTHESIS%20AND%20DEGRADATION%20OF%20POLY%20ALKYL%20ALPHA%20CYANOACRYLATES&rft.au=Leonard,%20Fred&rft.aucorp=ARMY%20MEDICAL%20BIOMECHANICAL%20RESEARCH%20LAB%20WALTER%20REED%20ARMY%20MEDICAL%20CENTER%20WASHINGTON%20D%20C&rft.date=1966-06&rft_id=info:doi/&rft_dat=%3Cdtic_1RU%3EAD0634617%3C/dtic_1RU%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |