FIBROUS PAPULE OF THE NOSE: A CLINICOPATHOLOGICAL STUDY

A clinicopathological study of 40 patients with a distinct isolated fibrous papule of the nose is reported. The histogenesis and pathogenesis of this unique tumor indicates the lesion probably represents the residual of a cellular nevus in which stromal elements persist because of the anatomical location. There is a microscopic similarity of the fibrous papule to facial lesions of adenoma sabaceum and solitary hamartomas. For this reason the possibility that the lesion could represent a hamartoma or unusual type of neural end organ tumor can not definitely be ruled out. We propose the name of fibrous papule for this benign dome-shaped tumor of the nose. Fibrous papule should be included in the differential diagnosis of lesions involving the nose, and particularly if the clinical characteristics are suggestive of a cellular nevus. Excision of the lesion flush with the surrounding skin is adequate treatment and allows for excellent cosmetic results. (Author) Pub. in Journal of Investigative Dermatology v45 n3 p194-203 1965 (Copies not available to DDC or Clearinghouse customers). Presented at Annual Meeting of The Society for Investigative Dermatology, Inc. (25th), San Francisco, Calif. 21-23 Jun 64.