TISSUE ENZYME RESPONSE TO COLD AND TO HYPERPHAGIA IN THE RAT
In rats exposed to cold (5C) for 14 days the activities of liver arginase, alanine-transaminase, and glucose-6phosphatase and of kidney phosphate-activated glutaminase were increased. In animals with a comparable hyperphagia due to bilateral ablation of the ventromedial region of the hypothalamus th...
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| creator | Beaton,John R Feleki,V |
| description | In rats exposed to cold (5C) for 14 days the activities of liver arginase, alanine-transaminase, and glucose-6phosphatase and of kidney phosphate-activated glutaminase were increased. In animals with a comparable hyperphagia due to bilateral ablation of the ventromedial region of the hypothalamus there was a smaller although significant increase in activity of kidney glutaminase but, in contrast to the effect of cold exposure, there was a significant decrease of liver alanine-transaminase activity and no apparent effect upon the activities of liver arginase or glucose-6-phosphatase. It is concluded that changes of enzyme activities in cold-exposed rats are not simply an adaptation to the increased nutrient flow consequent upon the hyperphagia induced. (Author)
Pub. in Canadian Journal of Physiology and Pharmacology, v42 p787-91 1964 (Copies available only to DDC users). |
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Pub. in Canadian Journal of Physiology and Pharmacology, v42 p787-91 1964 (Copies available only to DDC users).</description><language>eng</language><subject>ADAPTATION(PHYSIOLOGY) ; BODY WEIGHT ; CANADA ; CARBOHYDRATES ; COLD TOLERANCE ; ENZYMES ; EXPOSURE(PHYSIOLOGY) ; LIVER ; LOW TEMPERATURE ; METABOLISM ; RATS ; THALAMUS ; TISSUES(BIOLOGY)</subject><creationdate>1964</creationdate><rights>APPROVED FOR PUBLIC RELEASE</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,780,885,27567,27568</link.rule.ids><linktorsrc>$$Uhttps://apps.dtic.mil/sti/citations/AD0613106$$EView_record_in_DTIC$$FView_record_in_$$GDTIC$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Beaton,John R</creatorcontrib><creatorcontrib>Feleki,V</creatorcontrib><creatorcontrib>UNIVERSITY OF WESTERN ONTARIO LONDON</creatorcontrib><title>TISSUE ENZYME RESPONSE TO COLD AND TO HYPERPHAGIA IN THE RAT</title><description>In rats exposed to cold (5C) for 14 days the activities of liver arginase, alanine-transaminase, and glucose-6phosphatase and of kidney phosphate-activated glutaminase were increased. In animals with a comparable hyperphagia due to bilateral ablation of the ventromedial region of the hypothalamus there was a smaller although significant increase in activity of kidney glutaminase but, in contrast to the effect of cold exposure, there was a significant decrease of liver alanine-transaminase activity and no apparent effect upon the activities of liver arginase or glucose-6-phosphatase. It is concluded that changes of enzyme activities in cold-exposed rats are not simply an adaptation to the increased nutrient flow consequent upon the hyperphagia induced. (Author)
Pub. in Canadian Journal of Physiology and Pharmacology, v42 p787-91 1964 (Copies available only to DDC users).</description><subject>ADAPTATION(PHYSIOLOGY)</subject><subject>BODY WEIGHT</subject><subject>CANADA</subject><subject>CARBOHYDRATES</subject><subject>COLD TOLERANCE</subject><subject>ENZYMES</subject><subject>EXPOSURE(PHYSIOLOGY)</subject><subject>LIVER</subject><subject>LOW TEMPERATURE</subject><subject>METABOLISM</subject><subject>RATS</subject><subject>THALAMUS</subject><subject>TISSUES(BIOLOGY)</subject><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>1964</creationdate><recordtype>report</recordtype><sourceid>1RU</sourceid><recordid>eNrjZLAJ8QwODnVVcPWLivR1VQhyDQ7w9wt2VQjxV3D293FRcPRzAbE9IgNcgwI8HN09HRU8_RRCPIBKHUN4GFjTEnOKU3mhNDeDjJtriLOHbkpJZnJ8cUlmXmpJvKOLgZmhsaGBmTEBaQBZsCZP</recordid><startdate>19640616</startdate><enddate>19640616</enddate><creator>Beaton,John R</creator><creator>Feleki,V</creator><scope>1RU</scope><scope>BHM</scope></search><sort><creationdate>19640616</creationdate><title>TISSUE ENZYME RESPONSE TO COLD AND TO HYPERPHAGIA IN THE RAT</title><author>Beaton,John R ; Feleki,V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-dtic_stinet_AD06131063</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng</language><creationdate>1964</creationdate><topic>ADAPTATION(PHYSIOLOGY)</topic><topic>BODY WEIGHT</topic><topic>CANADA</topic><topic>CARBOHYDRATES</topic><topic>COLD TOLERANCE</topic><topic>ENZYMES</topic><topic>EXPOSURE(PHYSIOLOGY)</topic><topic>LIVER</topic><topic>LOW TEMPERATURE</topic><topic>METABOLISM</topic><topic>RATS</topic><topic>THALAMUS</topic><topic>TISSUES(BIOLOGY)</topic><toplevel>online_resources</toplevel><creatorcontrib>Beaton,John R</creatorcontrib><creatorcontrib>Feleki,V</creatorcontrib><creatorcontrib>UNIVERSITY OF WESTERN ONTARIO LONDON</creatorcontrib><collection>DTIC Technical Reports</collection><collection>DTIC STINET</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Beaton,John R</au><au>Feleki,V</au><aucorp>UNIVERSITY OF WESTERN ONTARIO LONDON</aucorp><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><btitle>TISSUE ENZYME RESPONSE TO COLD AND TO HYPERPHAGIA IN THE RAT</btitle><date>1964-06-16</date><risdate>1964</risdate><abstract>In rats exposed to cold (5C) for 14 days the activities of liver arginase, alanine-transaminase, and glucose-6phosphatase and of kidney phosphate-activated glutaminase were increased. In animals with a comparable hyperphagia due to bilateral ablation of the ventromedial region of the hypothalamus there was a smaller although significant increase in activity of kidney glutaminase but, in contrast to the effect of cold exposure, there was a significant decrease of liver alanine-transaminase activity and no apparent effect upon the activities of liver arginase or glucose-6-phosphatase. It is concluded that changes of enzyme activities in cold-exposed rats are not simply an adaptation to the increased nutrient flow consequent upon the hyperphagia induced. (Author)
Pub. in Canadian Journal of Physiology and Pharmacology, v42 p787-91 1964 (Copies available only to DDC users).</abstract><oa>free_for_read</oa></addata></record> |
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| source | DTIC Technical Reports |
| subjects | ADAPTATION(PHYSIOLOGY) BODY WEIGHT CANADA CARBOHYDRATES COLD TOLERANCE ENZYMES EXPOSURE(PHYSIOLOGY) LIVER LOW TEMPERATURE METABOLISM RATS THALAMUS TISSUES(BIOLOGY) |
| title | TISSUE ENZYME RESPONSE TO COLD AND TO HYPERPHAGIA IN THE RAT |
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