ELECTROPHORETIC MOBILITY AND ANTIGENICITY OF X-IRRADIATED HUMAN SERUM GAMMA GLOBULIN

EXPOSURE OF HSGG TO VARIOUS DOSES OF X-RAYS RESULTS IN THE PRODUCTION OF MOLECULES ELECTROPHORETICALLY DISTINCT FROM THE PARENT PROTEIN. THE EVIDENCE THAT STRUCTURAL CHANGES TAKE PLACE IS GIVEN SUPPORT BY THE FINDING THAT THE ANTIGENIC SPECIFICITY OF THE NEW DERIVATIVE IS FAR REMOVED FROM THAT OF TH...

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1. Verfasser: LUZZIO, ANTHONY J
Format: Report
Sprache:eng
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Zusammenfassung:EXPOSURE OF HSGG TO VARIOUS DOSES OF X-RAYS RESULTS IN THE PRODUCTION OF MOLECULES ELECTROPHORETICALLY DISTINCT FROM THE PARENT PROTEIN. THE EVIDENCE THAT STRUCTURAL CHANGES TAKE PLACE IS GIVEN SUPPORT BY THE FINDING THAT THE ANTIGENIC SPECIFICITY OF THE NEW DERIVATIVE IS FAR REMOVED FROM THAT OF THE STARTING MATERIAL. IT IS SUGGESTED THAT HSGG DENATURED BY IONIZING RAYS HAS DEFINITE AND CONTROLLABLE CHARACTERISTICS