Predictors of discordance between fractional flow reserve and instantaneous wave-free ratio in the real world

Invasive physiologic variables such as fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are used in clinical practice to assess the functional significance of epicardial coronary stenosis and guide the management. However, these two variables may show discrepancies when binary c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal Of The Saudi Heart Association 2018-10, Vol.30 (4), p.365-365
Hauptverfasser: Al-Dobai, Dikra, Balghith, Mohammad, Ayoub, Kamal, Enezi, Amira, Mahmud, Azra, Ghamdi, Ali AL
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Invasive physiologic variables such as fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are used in clinical practice to assess the functional significance of epicardial coronary stenosis and guide the management. However, these two variables may show discrepancies when binary cut-offs are used to decide for revascularization strategy. We investigated the clinical characteristics of lesions with discordance between iFR and FFR. 256 vessels (220 patients mean age 61 ± 12, 77% males) with available pre-intervention FFR and iFR values were included in the study. The vessels were classified according to FFR and iFR into concordant normal (Group 1 [n = 112]; FFR > 0.8 and iFR > 0.89); discordant with abnormal FFR and normal iFR (Group 2 [n = 12); FFR  0.89); discordant with normal FFR and abnormal iFR (Group 3 [n = 43], FFR > 0.8 and iFR 
ISSN:1016-7315
2212-5043
DOI:10.1016/j.jsha.2018.05.026