Complete Genome Sequence of Pseudomonas chloritidismutans 6L11 with Plant Growth–Promoting and Salt-Tolerant Properties
Objectives: To investigate the effect of epigalltechin-3-gallate(EGCG) on the alteration of morphology and the expression of nicotinamide phosphoribosy -ltransferase(NAMPT)after \u003csup\u003e131\u003c/sup\u003eI radiation in rat Parotid gland. Methods: The total 28 SD rats were randomly divided in...
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Veröffentlicht in: | Molecular plant-microbe interactions 2022-09, Vol.35 (9), p.870-874 |
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Zusammenfassung: | Objectives: To investigate the effect of epigalltechin-3-gallate(EGCG) on the alteration of morphology and the expression of nicotinamide phosphoribosy -ltransferase(NAMPT)after \u003csup\u003e131\u003c/sup\u003eI radiation in rat Parotid gland. Methods: The total 28 SD rats were randomly divided into four groups: the control group (n=7), the EGCG only group (n=7, EGCG was injected intraperitoneally, 100 mg/kg), the \u003csup\u003e131\u003c/sup\u003eI treated only group (n=9, \u003csup\u003e131\u003c/sup\u003eI was injected intraperitoneally,0.5 mci/100 g), and EGCG treatment with \u003csup\u003e131\u003c/sup\u003eI administration group. After administration of \u003csup\u003e131\u003c/sup\u003eI 7 days, hematoxylin-eosin staining observed the morphology change of Parotid glands microscope; immunohistochemical assay was used to detect the distribution and expression of NAMPT in Parotid gland. Results: \u003csup\u003e131\u003c/sup\u003eI resulted in vacuolization, atrophy and pyknotic nuclei in acinar cells, whereas treatment EGCG markedly alleviated acinar cell atrophy in Parotid grand. NAMPT was mainly expressed in cytoplasm and nucleus of serous acinar and duct cells, \u003csup\u003e131\u003c/sup\u003eI significantly decreased the expression of NAMPT nearly to the control level. Conclusions: These data indicated that EGCG could reduce the damage induced by \u003csup\u003e131\u003c/sup\u003eI in Parotid gland. which underlying mechanism might be related to the NAMPT upregulation by EGCG. |
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ISSN: | 0894-0282 1943-7706 |
DOI: | 10.1094/MPMI-01-22-0029-A |