Expression of Serum sLOX-1 in Patients with Non-Small-Cell Lung Cancer and Its Correlation with Lipid Metabolism

Objective. The aim of this study was to investigate the expression level of soluble LOX-1 (sLOX-1) in the serum of non-small-cell lung cancer (NSCLC) patients and its correlation with lipid metabolism. Methods. 99 inpatients with NSCLC and 81 healthy controls were enrolled in this study. The levels...

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Veröffentlicht in:	Canadian respiratory journal 2022-04, Vol.2022, p.6619331-9
Hauptverfasser:	Hao, Fangfang, Chen, Jinliang, Wu, Jinnan, Ge, Xin, Lv, Xuedong, Zhang, Dongmei, Chen, Jianrong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Carcinoembryonic Antigen - metabolism Carcinoma, Non-Small-Cell Lung Cardiovascular disease Care and treatment CEA (Oncology) Cell receptors Cholesterol Comparative analysis Development and progression Diagnosis Drug dosages Health aspects Health care Heart High density lipoprotein Hormone replacement therapy Hospital patients Hospitals Humans Lectins Lipid Metabolism Lipids Lipoproteins Lipoproteins, LDL - metabolism Low density lipoproteins Lung cancer Lung cancer, Non-small cell Lung Neoplasms Measurement Medical prognosis Metabolism Metastasis Normal distribution Physiological aspects Scavenger Receptors, Class E - metabolism Serodiagnosis Signal transduction Triglycerides Tumors
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Zusammenfassung:	Objective. The aim of this study was to investigate the expression level of soluble LOX-1 (sLOX-1) in the serum of non-small-cell lung cancer (NSCLC) patients and its correlation with lipid metabolism. Methods. 99 inpatients with NSCLC and 81 healthy controls were enrolled in this study. The levels of serum sLOX-1 were compared between the two groups, and the correlation of sLOX-1 with clinicopathological characteristics, blood lipid indices, and carcinoembryonic antigen was analyzed. Results. Compared with the healthy controls, sLOX-1, low-density lipoprotein, triglyceride, and carcinoembryonic antigen in the patients with NSCLC were significantly higher (p
ISSN:	1198-2241 1916-7245
DOI:	10.1155/2022/6619331