Prognostic value of preoperative albumin-to-alkaline phosphatase ratio in patients with surgically treated urological cancer: a systematic review and meta-analysis

Prognostic value of preoperative albumin-to-alkaline phosphatase ratio in patients with surgically treated urological cancer: a systematic review and meta-analysis

ObjectiveA novel albumin-to-alkaline phosphatase ratio (AAPR) is associated with the prognosis of several cancers. In the present study, we evaluate the prognostic significance of perioperative AAPR in urological cancers.MethodRelevant studies were searched comprehensively from CNKI, PubMed, Embase...

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Veröffentlicht in:Frontiers in oncology 2023-11, Vol.13, p.1236167-1236167
Hauptverfasser: Ren, Shangqing, Wang, Han, Yang, Bo, Zheng, Yang, Ou, Yong, Bao, Yige, Mao, Yu, Feng, Yunlin
Format: Artikel
Sprache:eng
Schlagworte:
albumin-to-alkaline phosphatase ratio
meta-analysis
prognostic value
surgical
urological cancer
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Zusammenfassung:ObjectiveA novel albumin-to-alkaline phosphatase ratio (AAPR) is associated with the prognosis of several cancers. In the present study, we evaluate the prognostic significance of perioperative AAPR in urological cancers.MethodRelevant studies were searched comprehensively from CNKI, PubMed, Embase and Web of Science up to March 2023. The pooled hazard ratio (HR) and 95% confidence interval (CI) were extracted from each study to evaluate the prognostic value of perioperative AAPR in patients with surgically treated urological cancers.ResultsA total of 8 studies consisting of 3,271 patients were included in the final results. A low AAPR was significantly associated with a worse OS (HR=2.21; P
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2023.1236167