Decision-making Impairments in Primary Angle-closure Glaucoma Patients

Background： Primary angle-closure glaucoma （PACG） is a common eye disease and a common cause of blindness. Inappropriate medical decisions severely affect the prognosis. This study investigated decision-making under risk in PACG patients.Methods： Thirty patients with first acute attack of PACG before surgery and thirty healthy controls were included in the study. Decision-making under risk was evaluated with the game of dice task （GDT）. The results of Eysenck Personality Questionnaire （EPQ） and GDT between PACG patients and healthy controls were compared. Results： Risky decisions in PACG patients were more than those in healthy controls as measured by mean score ofGDT （ 12.47 ±5.72 vs. 4.33± 3.30, P 〈 0.001）. Higher neuroticism score in EPQ was found in PACG patients compared to healthy controls （14.97 ± 3.93 vs. 9.90 ± 4.49, P 〈 0.001 ）. Neuroticism scores in EPQ were associated with decision-making performance （r = 0.417, P = 0.001 ）. Conclusions： Neuroticism positively correlated with risky decisions. Decision-making might be influenced by neuroticism. Future studies will show whether therapy compliance will be improved by emotional management and psychological intervention in PACG patients.