oposSOM-Browser: an interactive tool to explore omics data landscapes in health science

oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. These functionalities are now available as interactive web-browser application for a broader user audie...

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Veröffentlicht in:BMC bioinformatics 2020-10, Vol.21 (1), p.465-465, Article 465
Hauptverfasser: Loeffler-Wirth, Henry, Reikowski, Jasmin, Hakobyan, Siras, Wagner, Jonas, Binder, Hans
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Sprache:eng
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Zusammenfassung:oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular 'portrait landscapes', of associated phenotype diversity, and signalling pathway activation patterns. The oposSOM-Browser makes available interactive data browsing for five transcriptome data sets of cancer (melanomas, B-cell lymphomas, gliomas) and of peripheral blood (sepsis and healthy individuals) at www.izbi.uni-leipzig.de/opossom-browser .
ISSN:1471-2105
1471-2105
DOI:10.1186/s12859-020-03806-w