The screening of the compounds with antiaggregation activity among benzimidazole and xantine

The screening of the compounds with antiaggregation activity among benzimidazole and xantine

Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-lik...

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Veröffentlicht in:Vestnik Rossiĭskogo universiteta druzhby narodov. Serii͡a︡ Medit͡s︡ina 2008-12 (4), p.68-72
Hauptverfasser: G A Timirkhanova, А V Samorodov, Ye E Klyen, O Y Travnikov, D A Enikeyev, V А Katayev
Format: Artikel
Sprache:eng
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Zusammenfassung:Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising.
ISSN:2313-0245
2313-0261