Pediatric Open Long-Bone Fracture and Subsequent Deep Infection Risk: The Importance of Early Hospital Care

The purpose of the current study was to identify risk factors for deep infection after an open long-bone fracture in pediatric patients. Systematic billing queries were utilized to identify pediatric patients who presented to a level I trauma center from 1998 to 2019 with open long-bone fractures. There were 303 open long-bone fractures, and 24 (7.9%) of these became infected. Fractures of the tibia/fibula ( 0.022), higher revised Gustilo-Anderson type ( 0.017), and a longer duration of time between the injury and hospital presentation ( 0.008) were all associated with the presence of deep infection. Those who went on to have a deep infection also required more operative debridements ( 0.022) and a total number of operative procedures ( 0.026). The only factor that remained significant in multivariable regression was the duration between the injury and hospital presentation (OR 1.01 [95%CI 1.003-1.017]; 0.009), where the odds of deep infection increased by 1% for every minute of delayed presentation.