8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action

The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats.

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Veröffentlicht in:	Tonkie himičeskie tehnologii (Online) 2012-02, Vol.7 (1), p.59-63
Hauptverfasser:	D. S. Esipov, O. V. Esipova, T. V. Zinevich, T. A. Gorbacheva, T. S. Nevredimova, A. L. Krushinsky, V. S. Kuzenkov, V. P. Reutov
Format:	Artikel
Sprache:	rus
Schlagworte:	8-oxo-2'-deoxyguanosine acoustic stress amperometric detection cortexin hemorrhagic stroke oxidative stress reverse phase hplc
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Zusammenfassung:	The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats.
ISSN:	2410-6593 2686-7575