Predictive value of combined serum IL-6 with UREA on severity of neonatal pneumonia: an observational study

Predictive value of combined serum IL-6 with UREA on severity of neonatal pneumonia: an observational study

IL-6 is an inflammatory marker and urea nitrogen (UREA) is a common indicator of glomerular filtration function. Their combined detection has predictive value for the severity of neonatal pneumonia.We performed a cross-sectional analysis of the clinical and laboratory data, collected from 105 neonat...

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Veröffentlicht in:Journal of laboratory medicine 2023-12, Vol.47 (6), p.251-256
Hauptverfasser: Li, Ci, Xu, Zhe, Sun, Hongqi, Yang, Liu, Nie, Manjie, Gong, Weihua, Yang, Junmei, Li, Tiewei
Format: Artikel
Sprache:eng
Schlagworte:
Correlation analysis
il-6
Inflammation
Interleukin 6
neonatal pneumonia
Neonates
Observational studies
Pneumonia
Regression analysis
Risk factors
severe pneumonia
Urea
Ureas
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Zusammenfassung:IL-6 is an inflammatory marker and urea nitrogen (UREA) is a common indicator of glomerular filtration function. Their combined detection has predictive value for the severity of neonatal pneumonia.We performed a cross-sectional analysis of the clinical and laboratory data, collected from 105 neonatal patients (including 76 mild to moderate pneumonia patients and 29 severe pneumonia patients).Mann–Whitney U-test showed serum IL-6 and UREA levels were significantly increased in severe pneumonia, compared with that in mild to moderate pneumonia (p
ISSN:2567-9430
0342-3026
2567-9449
1439-0477
DOI:10.1515/labmed-2023-0077