Endometrial adenosarcoma in the setting of a germline DICER1 mutation: A case report

Endometrial adenosarcoma in the setting of a germline DICER1 mutation: A case report

Highlights • DICER1 mutations play a significant role in gynecologic malignancy. • DICER1 may be involved in the sarcomagenesis of endometrial adenosarcoma. • The knowledge of a genetic mutation can help clarify a patient's medical history.

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Bibliographische Detailangaben
Veröffentlicht in:Gynecologic oncology reports 2017-05, Vol.20 (C), p.121-124
Hauptverfasser: Mullen, Mary M, Divine, Laura M, Hagemann, Ian S, Babb, Sheri, Powell, Matthew A
Format: Artikel
Sprache:eng
Schlagworte:
Case Report
DICER1 gene
Endometrial cancer
Germline mutation
Hematology, Oncology and Palliative Medicine
Mullerian adenosarcoma
Obstetrics and Gynecology
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Beschreibung
Zusammenfassung:Highlights • DICER1 mutations play a significant role in gynecologic malignancy. • DICER1 may be involved in the sarcomagenesis of endometrial adenosarcoma. • The knowledge of a genetic mutation can help clarify a patient's medical history.
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2017.04.004