Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury

Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury

Our study aimed to investigate the role of endoplasmic reticulum stress (ER) in brain damage following hepatic ischemia-reperfusion (HIR) injury. Specifically, we characterized the expression of markers of ER stress and histopathologic changes in the brain following HIR.

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Veröffentlicht in:Türk biyokimya dergisi 2023-06, Vol.48 (4), p.432-439
Hauptverfasser: Karademir, Mustafa, Doğan, Halef O., Sahin İnan, Zeynep Deniz, Doğan, Kübra, Kablan, Demet
Format: Artikel
Sprache:eng
Schlagworte:
ATF-4
brain damage
ER stress
GRP-78
hepatic ischemia-reperfusion
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Zusammenfassung:Our study aimed to investigate the role of endoplasmic reticulum stress (ER) in brain damage following hepatic ischemia-reperfusion (HIR) injury. Specifically, we characterized the expression of markers of ER stress and histopathologic changes in the brain following HIR.
ISSN:1303-829X
1303-829X
DOI:10.1515/tjb-2022-0292