IMPULSE: the impact of gender on the presentation and management of aortic stenosis across Europe

AimsThere is an increasing awareness of gender-related differences in patients with severe aortic stenosis and their outcomes after surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI).MethodsData from the IMPULSE registry were analysed. Patients with severe ao...

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Veröffentlicht in:	Open heart 2021-01, Vol.8 (1), p.e001443
Hauptverfasser:	Steeds, Richard Paul, Messika-Zeitoun, David, Thambyrajah, Jeetendra, Serra, Antonio, Schulz, Eberhard, Maly, Jiri, Aiello, Marco, Rudolph, Tanja K, Lloyd, Guy, Bortone, Alessandro Santo, Clerici, Alberto, Delle-Karth, Georg, Rieber, Johannes, Indolfi, Ciro, Mancone, Massimo, Belle, Loic, Lauten, Alexander, Arnold, Martin, Bouma, Berto J, Lutz, Matthias, Deutsch, Cornelia, Kurucova, Jana, Thoenes, Martin, Bramlage, Peter, Frey, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Chronic obstructive pulmonary disease Ejection fraction Females Gender differences Heart surgery Hematology Liver diseases Patients Population Sensitivity analysis Surgical outcomes Valvular Heart Disease Women
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Zusammenfassung:	AimsThere is an increasing awareness of gender-related differences in patients with severe aortic stenosis and their outcomes after surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI).MethodsData from the IMPULSE registry were analysed. Patients with severe aortic stenosis (AS) were enrolled between March 2015 and April 2017 and stratified by gender. A subgroup analysis was performed to assess the impact of age.ResultsOverall, 2171 patients were enrolled, and 48.0% were female. Women were characterised by a higher rate of renal impairment (31.7 vs 23.3%; p
ISSN:	2053-3624 2398-595X 2053-3624
DOI:	10.1136/openhrt-2020-001443