Dermatitis herpetiformis Duhring – case report

Dermatitis herpetiformis (DH) is rare, persistent an autoimmune itchy skin eruption associated with gluten sensitive disorder. DH is characterized by grouped excoriations, erythematous, urticarial plaques, and papules with vesicles. We present a case of 15th years old young man with first skin lesions started five years ago as erythematous rush on elbows and knees. Our patient had, after few months, eruption erythematous plaques on the skin of the extensor side upper and lower extremities, back, neck and both gluteal region. Therapy: Gluten-free diet, methylprednisolone 40mg i.m. 10 days, then 36mg per os in the morning 5 days, and reduce dose methylprednisolone every 5 days for 4 mg less, Ranitidin tabl 150 mg 2×1,Thopical therapy: Alklometazon ung 2x. After one month, our patient had good regression skin lesion and less pruritus and sistemic therapy with methyprednisolone was excluded, with significant clinical improvement, without new lesions and without DH lesions after six monts.Gluten-free diet is control of the cutaneous manifestations of DH in most patients. Pharmacotherapy used to treat DH are Dapsone and sulfapyridine like the primary medication. Other medication include systemic corticosteroid therapy, colchicine, cyclosporine, and azathioprine.