Utility of 1,2‐o‐dilauryl‐rac‐glycero glutaric acid‐(6′‐methylresorufin)‐ester‐lipase for monitoring dogs with chronic pancreatitis

Background The utility of 1,2‐o‐dilauryl‐rac‐glycero glutaric acid‐(6′‐methylresorufin)‐ester‐(DGGR)‐lipase activity (DLA) in monitoring clinical progression of chronic pancreatitis (CP) in dogs is unknown. Objective To examine the association of DLA with clinical signs of CP, as assessed by a CP clinical severity score (CPCSS). Animals: Twenty‐four dogs. Methods This is a retrospective study. Chronic pancreatitis was diagnosed based on clinical signs and DLA > 250 U/L and monitored using CPCSS and DLA. Results The study included 134 visits (median, 10 visits/dog; range, 2‐11). Mild‐moderate (CPCSS, 0‐3) and severe (CPCSS, ≥4) disease were documented in 94 (70%) and 40 (30%) visits, respectively. In emergency visits (n = 44; 33%) CPCSS (median, 5; range, 0‐15) and DLA (median, 534 U/L; range, 63‐7133) were higher (P