Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities

The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant com...

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Veröffentlicht in:Saudi pharmaceutical journal 2017-07, Vol.25 (5), p.703-708
Hauptverfasser: Demirci, Betul, Yusufoglu, Hasan Soliman, Tabanca, Nurhayat, Temel, Halide Edip, Bernier, Ulrich R., Agramonte, Natasha M., Alqasoumi, Saleh Ibrahim, Al-Rehaily, Adnan Jathlan, Başer, Kemal Husnu Can, Demirci, Fatih
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Sprache:eng
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Zusammenfassung:The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant compounds were camphene (38.5%), myrcene (17.5%), limonene (10.1%) and α-pinene (8.7%). Referring to the ethnobotanical utilization, an insecticidal assay was performed, where the oil repelled the yellow fever mosquito Aedes aegypti L. at a minimum effective dose (MED of 0.035±0.010mg/cm2) compared to the positive control DEET (MED of 0.015±0.004mg/cm2). Additionally, the in vitro antimicrobial activity against a panel of pathogens was determined using a microdilution method. The acetyl- and butyrylcholine esterase inhibitory activities were measured using the colorimetric Ellman method. The bioassay results showed that the oil was rather moderate in antimicrobial and cholinesterase inhibitions when compared to the standard compounds.
ISSN:1319-0164
2213-7475
DOI:10.1016/j.jsps.2016.10.009