Therapeutic outcome and related predictors of stereotactic body radiotherapy for small liver-confined HCC: a systematic review and meta-analysis of observational studies

Background and purpose Stereotactic body radiotherapy (SBRT) is a promising ablative modality for hepatocellular carcinoma (HCC) especially for those with small-sized or early-stage tumors. This study aimed to synthesize available data to evaluate efficacy and explore related predictors of SBRT for...

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Veröffentlicht in:	Radiation oncology (London, England) England), 2021-04, Vol.16 (1), p.68-15, Article 68
Hauptverfasser:	Long, Yanyan, Liang, Yan, Li, Shujie, Guo, Jing, Wang, Ying, Luo, Yan, Wu, Yongzhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Adult Age Aged Aged, 80 and over Cancer therapies Carcinoma, Hepatocellular - radiotherapy Care and treatment Clinical trials Complications Confidence intervals Development and progression Evaluation Female Hepatocellular carcinoma Hepatocellular carcinoma (HCC) Hepatoma Humans Lesions Life Sciences & Biomedicine Liver Liver - pathology Liver cancer Liver Neoplasms - radiotherapy Lymphatic system Male Medical prognosis Meta-analysis Metastasis Methods Middle Aged Observational studies Observational Studies as Topic Oncology Patient outcomes Patients Prognosis Radiation Radiation dosage Radiation therapy Radiology, Nuclear Medicine & Medical Imaging Radiosurgery - methods Radiotherapy Science & Technology Statistical analysis Statistical methods Stereotactic body radiotherapy (SBRT) Subgroups Systematic review Toxicity Treatment Outcome Tumors
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Zusammenfassung:	Background and purpose Stereotactic body radiotherapy (SBRT) is a promising ablative modality for hepatocellular carcinoma (HCC) especially for those with small-sized or early-stage tumors. This study aimed to synthesize available data to evaluate efficacy and explore related predictors of SBRT for small liver-confined HCC (
ISSN:	1748-717X 1748-717X
DOI:	10.1186/s13014-021-01761-1