TP53 rs1042522 polymorphism and early-onset breast cancer

TP53 rs1042522 polymorphism and early-onset breast cancer

Background: Breast cancer is the leading cause of cancer deaths among women. Early-onset breast cancer is well recognized as it clinically differs from old-age diagnosed breast neoplasms. TP53 rs1042522 polymorphism relates to the risk of breast neoplasms, but this relationship in Turkish early-onse...

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Veröffentlicht in:Journal of research in medical sciences 2020-01, Vol.25 (1), p.25-25, Article 25
Hauptverfasser: Icen-Taskin, Irmak, Irtegun-Kandemir, Sevgi, Munzuroglu, Omer
Format: Artikel
Sprache:eng
Schlagworte:
Age
Breast cancer
breast neoplasms
Cancer therapies
Cell cycle
Deoxyribonucleic acid
DNA
early onset
Ethnicity
Family medical history
Gene expression
General & Internal Medicine
Genetic aspects
genotype
Genotype & phenotype
Health risk assessment
Life Sciences & Biomedicine
Medical research
Medicine, General & Internal
Original
Patients
Polymorphism
rs1042522
Science & Technology
Studies
tp53
Tumor proteins
Tumors
Women's health
Womens health
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Zusammenfassung:Background: Breast cancer is the leading cause of cancer deaths among women. Early-onset breast cancer is well recognized as it clinically differs from old-age diagnosed breast neoplasms. TP53 rs1042522 polymorphism relates to the risk of breast neoplasms, but this relationship in Turkish early-onset breast cancer patients has not been investigated yet. We aimed to search the relationship between TP53 rs1042522 polymorphism and young Turkish breast cancer patients. Materials and Methods: Ninety-six female breast cancer patients who were
ISSN:1735-1995
1735-7136
DOI:10.4103/jrms.JRMS_506_19