Sweet Syndrome in Early Infancy

Sweet syndrome (SS), also known as acute febrile neutrophilic dermatosis, is an uncommon inflammatory disease in pediatrics. It presents with fever, blood neutrophilia, and painful erythematous plaques with a dermal neutrophilic infiltrate. In general, it is associated with infections, hematologic and solid tumor, immunodeficiency, and certain drugs. It can easily be mistaken for infection and can lead to prescribe antibiotics or antiviral agents. Here, we describe a case of a 6-week-old infant who developed SS following a pulmonary infection. The patient presented with ocular manifestations and fully recovered after 1 week of corticosteroids.