Stress Hormone and Oxidative Stress Biomarkers Link Obesity and Diabetes with Reduced Fertility Potential

Tilting the balance in favor of antioxidant agents could increase infertility problems in obese and diabetic individuals. The aim of this study was to evaluate oxidative stress status in semen of men with type 2 diabetes and obesity to investigate whether excessive amounts of oxidative stress, as a...

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Veröffentlicht in:	Cell journal (Yakhteh) 2019-10, Vol.21 (3), p.307-313
Hauptverfasser:	Abbasihormozi, S Hima, Babapour, Vahab, Kouhkan, Azam, Niasari Naslji, Amir, Afraz, Kaveh, Zolfaghary, Zahra, Shahverdi, Abdol Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Apoptosis Biomarkers Body mass index Control methods Cortisol Deoxyribonucleic acid Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) DNA DNA fragmentation Enzyme-linked immunosorbent assay Epidemiology Fertility Flow cytometry Fragmentation Glucose Hemoglobin Hormones Infertility Levels Male Infertility Metabolic disorders Morphology Motility Obesity Original Oxidation Oxidative stress Physicians Reactive Oxygen Species Research centers Semen Software Sperm Testosterone Veterinary medicine
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Zusammenfassung:	Tilting the balance in favor of antioxidant agents could increase infertility problems in obese and diabetic individuals. The aim of this study was to evaluate oxidative stress status in semen of men with type 2 diabetes and obesity to investigate whether excessive amounts of oxidative stress, as a result of diabetes and obesity, influence infertility potential. A case-control study was conducted in men (n=150) attending the Infertility Center of Royan Institute between December 2016 and February 2017. Participants were categorized into four groups; normal weight (BMI
ISSN:	2228-5806 2228-5814
DOI:	10.22074/cellj.2019.6339