Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil

In 2014, the first cases of autochthonous chikungunya (CHIK) were recorded in Brazil. Lethality associated with this disease is underestimated. Thus, this study aimed to analyze the causes of death among individuals with CHIK in Brazil. A descriptive observational study was conducted on individuals...

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Veröffentlicht in:Revista da Sociedade Brasileira de Medicina Tropical 2020-01, Vol.53, p.e20190580-e20190580
Hauptverfasser: Frutuoso, Livia Carla Vinhal, Freitas, André Ricardo Ribas, Cavalcanti, Luciano Pamplona de Góes, Duarte, Elisabeth Carmen
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Sprache:eng
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Zusammenfassung:In 2014, the first cases of autochthonous chikungunya (CHIK) were recorded in Brazil. Lethality associated with this disease is underestimated. Thus, this study aimed to analyze the causes of death among individuals with CHIK in Brazil. A descriptive observational study was conducted on individuals with CHIK who died within 6 months from symptom onset. Data pairing between the Information System for Notifiable Diseases and the Mortality Information System was performed. Deaths were classified according to case confirmation criterion, mention of CHIK in the death certificates (DCs), and disease phase. The lethality rate per 1,000 cases was corrected for underreporting and was estimated according to region, sex, age, years of education, race/color, and cause groups. We identified 3,135 deaths (mention of CHIK in the DCs, 764 [24.4%]). In 17.6% of these cases, CHIK was the underlying cause. Most deaths occurred in the acute (38.1%) and post-acute (29.6%) phases. The corrected LR (5.7; x1,000) was 6.8 times higher than that obtained from the Information System for Notifiable Diseases (0.8). The highest corrected LRs were estimated for among individuals living in the Northeast region (6.2), men (7.4), those with low years of education and those aged
ISSN:0037-8682
1678-9849
1678-9849
DOI:10.1590/0037-8682-0580-2019