Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone

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Veröffentlicht in:	Haematologica (Roma) 2017-04, Vol.102 (4), p.e120-e124
Hauptverfasser:	Lidonnici, Maria Rosa, Aprile, Annamaria, Frittoli, Marta Claudia, Mandelli, Giacomo, Paleari, Ylenia, Spinelli, Antonello, Gentner, Bernhard, Zambelli, Matilde, Parisi, Cristina, Bellio, Laura, Cassinerio, Elena, Zanaboni, Laura, Cappellini, Maria Domenica, Ciceri, Fabio, Marktel, Sarah, Ferrari, Giuliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD34 - genetics Antigens, CD34 - immunology beta-Thalassemia - genetics beta-Thalassemia - immunology beta-Thalassemia - pathology beta-Thalassemia - therapy Cell Cycle Proteins - genetics Cell Cycle Proteins - immunology Chemokine CXCL12 - genetics Chemokine CXCL12 - immunology Drug Combinations Endonucleases - genetics Endonucleases - immunology Gene Expression Profiling Gene Expression Regulation Granulocyte Colony-Stimulating Factor - pharmacology Hematopoietic Stem Cell Mobilization - methods Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Heterocyclic Compounds - pharmacology Humans Immunophenotyping Leukapheresis Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - immunology Mice Online Only Protein Binding Receptors, CXCR4 - genetics Receptors, CXCR4 - immunology Signal Transduction Stem Cell Niche - immunology
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