Does muscle invasive bladder cancer following pelvic radiotherapy portend worse prognosis? A seer-based study

Although emerging evidence demonstrates increased risk of secondary bladder cancer following pelvic radiotherapy, the aggressiveness of these tumors is not well-characterized. A search of the Surveillance, Epidemiology, and End Results (SEER) 18 Database, identified 25,734 patients diagnosed with bl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer treatment and research communications 2020, Vol.24, p.100177, Article 100177
Hauptverfasser:	Natale, Caleb, Leinwand, Gabriel, Zeineddine, Farid, Silberstein, Jonathan L, Krane, Louis S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bladder cancer Carcinoma, Transitional Cell - etiology Carcinoma, Transitional Cell - mortality Carcinoma, Transitional Cell - pathology Female Humans Kaplan-Meier Estimate Male Middle Aged Neoplasm Grading Neoplasms, Radiation-Induced - etiology Neoplasms, Radiation-Induced - mortality Neoplasms, Second Primary - etiology Neoplasms, Second Primary - mortality Neoplasms, Second Primary - pathology Pelvic cancer Prognosis Prostatic Neoplasms - therapy Radiotherapy Radiotherapy, Adjuvant - adverse effects Retrospective Studies Second primary cancer SEER SEER Program - statistics & numerical data Time Factors Urinary Bladder - pathology Urinary Bladder - radiation effects Urinary Bladder Neoplasms - etiology Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology Uterine Cervical Neoplasms - therapy Uterine Neoplasms - therapy Vaginal Neoplasms - therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Although emerging evidence demonstrates increased risk of secondary bladder cancer following pelvic radiotherapy, the aggressiveness of these tumors is not well-characterized. A search of the Surveillance, Epidemiology, and End Results (SEER) 18 Database, identified 25,734 patients diagnosed with bladder cancer following definitive therapy for previous pelvic malignancy. Kaplan-Meier curve analyses were utilized to determine overall survival with significance set at p
ISSN:	2468-2942 2468-2942
DOI:	10.1016/j.ctarc.2020.100177