Higher Levels of Serum Uric Acid Have a Significant Association with Lower Incidence of Lower Urinary Tract Symptoms in Healthy Korean Men

Higher Levels of Serum Uric Acid Have a Significant Association with Lower Incidence of Lower Urinary Tract Symptoms in Healthy Korean Men

Gout has been correlated with the risk of incident benign prostatic hyperplasia. In line with increasing prevalence of hyperuricemia, the aim of this study was to investigate the relationship between serum uric acid (SUA) level and the incidence of lower urinary tract symptoms (LUTS) among clinicall...

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Veröffentlicht in:Metabolites 2022-07, Vol.12 (7), p.649
Hauptverfasser: Hwang, Jiwon, Ryu, Seungho, Ahn, Joong Kyong
Format: Artikel
Sprache:eng
Schlagworte:
Age
Alcohol
Blood pressure
Body mass index
Cell growth
Cholesterol
Comorbidity
Diabetes
Gout
Homeostasis
Hyperplasia
Hypertension
Hyperuricemia
Insulin resistance
Investigations
lower urinary tract symptoms
men
Metabolic syndrome
Metabolites
Oxidative stress
Prostate
Prostate cancer
Rheumatism
Uric acid
Urinary tract
Urogenital system
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Zusammenfassung:Gout has been correlated with the risk of incident benign prostatic hyperplasia. In line with increasing prevalence of hyperuricemia, the aim of this study was to investigate the relationship between serum uric acid (SUA) level and the incidence of lower urinary tract symptoms (LUTS) among clinically healthy middle-aged men. We performed a cohort study in 101,091 Korean men without LUTS at baseline who completed health checkups between 2011 and 2016. LUTS were evaluated using the International Prostate Symptom Score, where a score ≥ 8 was defined as significant LUTS. Men were divided into six groups according to their SUA levels in mg/dL (
ISSN:2218-1989
2218-1989
DOI:10.3390/metabo12070649