Primary Cutaneous Mantle Cell Lymphoma: A Case Report

Primary Cutaneous Mantle Cell Lymphoma: A Case Report

Primary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic...

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Veröffentlicht in:Case reports in dermatological medicine 2013-01, Vol.2013 (2013), p.1-3
Hauptverfasser: Bravo, A. I., Sorin, I., Castro Perez, G. A., Mazzuoccolo, L. D.
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Sprache:eng
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Case Report
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Zusammenfassung:Primary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic options. In this case, we describe the clinical, histopathological, immunohistochemical, and molecular characteristics of a new case of primary cutaneous MCL.
ISSN:2090-6463
2090-6471
DOI:10.1155/2013/394596