Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?

Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article perf...

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Veröffentlicht in:	Diagnostic and interventional radiology (Ankara, Turkey) Turkey), 2016-01, Vol.22 (1), p.75-89
Hauptverfasser:	García-Figueiras, Roberto, Baleato-González, Sandra, Padhani, Anwar R, Oleaga, Laura, Vilanova, Joan C, Luna, Antonio, Cobas Gómez, Juan Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Evaluation Humans Image acquisition Magnetic resonance spectroscopy Metabolites Neoplasms - diagnostic imaging Neoplasms - metabolism Oncologic Imaging Prognosis Proton magnetic resonance Proton Magnetic Resonance Spectroscopy - methods Sensitivity and Specificity Spectrum analysis Tumors
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Beschreibung
Zusammenfassung:	Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
ISSN:	1305-3825 1305-3612
DOI:	10.5152/dir.2015.15009