Clinical profile and containment of the Ebola virus disease outbreak in two large West African cities, Nigeria, July–September 2014

Highlights • The outbreak, mostly a severe febrile gastroenteritis syndrome (85% fever, 70% fatigue, 65% diarrhea, 50% vomiting), was in keeping with the West Africa Ebola virus disease pattern.. • It began in Africa's most populous city and spread to a second largest city, but involved only 20 cases, mostly females and health workers; no case management worker was infected. • The case fatality rate was low at 40%. • A higher mortality was seen in males, those in the older age group (≥40 years), patients with diarrhea, vomiting, or bleeding, and those presenting late to the treatment center. • Early case identification (survivors 3 ± 2 days, non-survivors 5 ± 2 days) due to effective contact tracing by epidemiologists/trainee epidemiologists, as well as prompt suspected case evaluation/isolation achieved containment within 2 months.