Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways-5

Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways-5

measured by flowcytometry as described in the Material and Methods. The shift-down of fluorescence from Red to Green indicates the collapse of mitochondrial membrane potential. CCCP was used as a positive control for the disruption of mitochondrial membrane potential. The percent of cells with the d...

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Hauptverfasser: Quanyi Lu, Xianghua Lin, Feng, Jean, Xiangmin Zhao, Gallagher, Ruth, Lee, Marietta Y, Jen-Wei Chiao, Delong Liu
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creator Quanyi Lu
Xianghua Lin
Feng, Jean
Xiangmin Zhao
Gallagher, Ruth
Lee, Marietta Y
Jen-Wei Chiao
Delong Liu
description measured by flowcytometry as described in the Material and Methods. The shift-down of fluorescence from Red to Green indicates the collapse of mitochondrial membrane potential. CCCP was used as a positive control for the disruption of mitochondrial membrane potential. The percent of cells with the disruption of mitochondrial membrane potential was indicated.Copyright information:Taken from "Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways"http://www.jhoonline.org/content/1/1/6Journal of Hematology and Oncology 2008;1():6-6.Published online 9 Jun 2008PMCID:PMC2438442.
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title Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways-5
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