WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death

Mutations in the macroautophagy/autophagy gene WDR45 cause β-propeller protein-associated neurodegeneration (BPAN); however the molecular and cellular mechanism of the disease process is largely unknown. Here we generated constitutive wdr45 knockout (KO) mice that displayed cognitive impairments, ab...

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Hauptverfasser:	Wan, Huida, Wang, Qi, Chen, Xiuting, Zeng, Qiufang, Shao, Yanjiao, Fang, Houqin, Liao, Xun, Li, Hu-Song, Liu, Ming-Gang, Xu, Tian-Le, Diao, Miaomiao, Li, Dali, Meng, Bo, Tang, Bin, Zhang, Zhuohua, Liao, Lujian
Format:	Dataset
Sprache:	eng
Schlagworte:	Biochemistry Cell Biology FOS: Biological sciences Genetics Mental Health Molecular Biology Neuroscience
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